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Leviticus 14:50

Albert Barnes
Notes on the Whole Bible
Verses 33-53

This section is separated from that on leprosy in clothing Leviticus 13:47-59 with which it would seem to be naturally connected, and is placed last of all the laws concerning leprosy, probably on account of its being wholly prospective. While the Israelites were in the wilderness, the materials of their dwellings were of nearly the same nature as those of their clothing, and would be liable to the same sort of decay. They were therefore included under the same law.

I put the plague - Yahweh here speaks as the Lord of all created things, determining their decay and destruction as well as their production. Compare Isaiah 45:6-7; Jonah 4:7; Matthew 21:20.

Leviticus 14:37

Hollow strakes … - Rather, depressed spots of dark green or dark red, appearing beneath (the surface of) the wall.

Leviticus 14:49

Cleanse the house - Strictly, “purge the house from sin.” The same word is used in Leviticus 14:52; and in Leviticus 14:53 it is said, “and make an atonement for it.” Such language is used figuratively when it is applied to things, not to persons. The leprosy in houses, the leprosy in clothing, and the terrible disease in the human body, were representative forms of decay which taught the lesson that all created things, in their own nature, are passing away, and are only maintained for their destined uses during an appointed period, by the power of Yahweh.

Matthew Henry
Concise Bible Commentary
The leprosy in a house is unaccountable to us, as well as the leprosy in a garment; but now sin, where that reigns in a house, is a plague there, as it is in a heart. Masters of families should be aware, and afraid of the first appearance of sin in their families, and put it away, whatever it is. If the leprosy is got into the house, the infected part must be taken out. If it remain in the house, the whole must be pulled down. The owner had better be without a dwelling, than live in one that was infected. The leprosy of sin ruins families and churches. Thus sin is so interwoven with the human body, that it must be taken down by death.