Zion spreadeth forth her hands - Extending the hands is the form in supplication.
Jerusalem is as a menstruous woman - To whom none dared to approach, either to help or comfort, because of the law, Leviticus 15:19-27.
Spreadeth forth her hands - In prayer Exodus 9:29, Exodus 9:33, but Zion entreats in vain. There is no one to comfort her - not God, for He is chastising her, nor man, for all the neighboring nations have become her enemies. See Lamentations 1:2.
That his adversaries - Rather, that those round about him should be his adversaries; all the neighboring states should regard him with aversion.
Jerusalem is - i. e. is become an abomination. The words are virtually the same as in Lamentations 1:8.