I cry unto thee - I am persecuted by man, afflicted with sore disease, and apparently forsaken of God.
I stand up - Or, as some translate, "I persevere, and thou lookest upon me." Thou seest my desolate, afflicted state; but thine eye doth not affect thy heart. Thou leavest me unsupported to struggle with my adversities.
I cry unto thee, and thou dost not hear me - This was a complaint which Job often made, that he could not get the ear of God; that his prayer was not regarded, and that he could not get his cause before him; compare Job 13:3, Job 13:19 ff, and Job 27:9.
I stand up - Standing was a common posture of prayer among the ancients; see Hebrews 11:21; 1 Kings 8:14, 1 Kings 8:55; Nehemiah 9:2. The meaning is, that when Job stood up to pray, God did not regard his prayer.