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Tychicus have I sent to Ephesus - For this person, see Acts 20:4; Ephesians 6:21; Colossians 4:7. It is rather strange that the apostle should say, I have sent Tychicus to Ephesus, if Timothy was at Ephesus at this time; but it is probable that Tychicus had been sent to Ephesus some time before this, and therefore the apostle might say, though writing now to Ephesus, Tychicus have I sent, etc.

And Tychicus - See Acts 20:4. In Ephesians 6:21, Paul calls him “a beloved brother, and faithful minister in the Lord.” But it may be asked why he did not retain him with him, or why should he have sent him away, and then call Timothy to him? The probability is, that he had sent him before he had seen reason to apprehend that he would be put to death; and now, feeling the need of a friend to be with him, he sent to Timothy, rather than to him, because Tychicus had been employed to perform some service which he could not well leave, and because Paul wished to give some some special instructions to Timothy before he died.

Have I sent to Ephesus - Why, is not certainly known; compare Intro. Section 2.

Since the earlier years of his profession of faith, Mark's Christian experience had deepened. As he had studied more closely the life and death of Christ he had obtained clearer views of the Saviour's mission, its toils and conflicts. Reading in the scars in Christ's hands and feet the marks of His service for humanity, and the length to which self-abnegation leads to save the lost and perishing, Mark had become willing to follow the Master in the path of self-sacrifice. Now, sharing the lot of Paul the prisoner, he understood better than ever before that it is infinite gain to win Christ, infinite loss to win the world and lose the soul for whose redemption the blood of Christ was shed. In the face of severe trial and adversity, Mark continued steadfast, a wise and beloved helper of the apostle. AA 455.1

Demas, steadfast for a time, afterward forsook the cause of Christ. In referring to this, Paul wrote, “Demas hath forsaken me, having loved this present world.” 2 Timothy 4:10. For worldly gain, Demas bartered every high and noble consideration. How shortsighted the exchange! Possessing only worldly wealth or honor, Demas was poor indeed, however much he might proudly call his own; while Mark, choosing to suffer for Christ's sake, possessed eternal riches, being accounted in heaven an heir of God and a joint heir with His Son. AA 455.2

Among those who gave their hearts to God through the labors of Paul in Rome was Onesimus, a pagan slave who had wronged his master, Philemon, a Christian believer in Colosse, and had escaped to Rome. In the kindness of his heart, Paul sought to relieve the poverty and distress of the wretched fugitive and then endeavored to shed the light of truth into his darkened mind. Onesimus listened to the words of life, confessed his sins, and was converted to the faith of Christ. AA 456.1

Upon his arrival at Rome, Paul was placed in a gloomy dungeon, there to remain until his course should be finished. Accused of instigating one of the basest and most terrible of crimes against the city and the nation, he was the object of universal execration. AA 490.1

The few friends who had shared the burdens of the apostle, now began to leave him, some by desertion, and others on missions to the various churches. Phygellus and Hermogenes were the first to go. Then Demas, dismayed by the thickening clouds of difficulty and danger, forsook the persecuted apostle. Crescens was sent by Paul to the churches of Galatia, Titus to Dalmatia, Tychicus to Ephesus. Writing to Timothy of this experience, Paul said, “Only Luke is with me.” 2 Timothy 4:11. Never had the apostle needed the ministrations of his brethren as now, enfeebled as he was by age, toil, and infirmities, and confined in the damp, dark vaults of a Roman prison. The services of Luke, the beloved disciple and faithful friend, were a great comfort to Paul and enabled him to communicate with his brethren and the world without. AA 490.2

In this trying time Paul's heart was cheered by frequent visits from Onesiphorus. This warmhearted Ephesian did all in his power to lighten the burden of the apostle's imprisonment. His beloved teacher was in bonds for the truth's sake, while he himself went free, and he spared himself no effort to make Paul's lot more bearable. AA 490.3

Paul concluded his letter with personal messages to different ones and again repeated the urgent request that Timothy come to him soon, if possible before the winter. He spoke of his loneliness, caused by the desertion of some of his friends and the necessary absence of others; and lest Timothy should hesitate, fearing that the church at Ephesus might need his labors, Paul stated that he had already dispatched Tychicus to fill the vacancy. AA 508.1

After speaking of the scene of his trial before Nero, the desertion of his brethren, and the sustaining grace of a covenant-keeping God, Paul closed his letter by commending his beloved Timothy to the guardianship of the Chief Shepherd, who, though the undershepherds might be stricken down, would still care for His flock. AA 508.2

We call on you to take your Bible, but do not put a sacrilegious hand upon it, and say, “That is not inspired,” simply because somebody else has said so. Not a jot or tittle is ever to be taken from that Word. Hands off, brethren! Do not touch the ark. Do not lay your hand upon it, but let God move. It is with His own power, and He will work in such a manner that He will compass our salvation. We want God to have some room to work. We do not want man's ideas to bind Him about. 7BC 920.1

I know something of the glory of the future life. Once a sister wrote to me and asked if I would not tell her something about the city of our God, further than we have in the Word. She asked me if I could not draw something of its plans. I wrote her that I would have to say to her, “Put off thy shoes from off thy feet, for the place whereon thou standest is holy ground.” “No,” said I, “you cannot paint, you cannot picture, and the martyr tongue cannot begin to give any description of the glory of the future life; but I will tell you what you can do: you can ‘press toward the mark for the prize of the high calling of God in Christ Jesus.’ You can die to self; you can seek to grow up to the perfection of Christian character in Christ Jesus.” That is our work; but when men begin to meddle with God's Word, I want to tell them to take their hands off, for they do not know what they are doing (Manuscript 13, 1888). 7BC 920.2