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Destruction and misery are in their ways - destruction is their work, and Misery to themselves and to the objects of their malice is the consequence of their impious and murderous conduct.

Destruction - That is, they “cause” the destruction or the ruin of the reputation, happiness, and peace of others.

Misery - Calamity, ruin.

In their ways - Wherever they go. This is a striking description not only of the wicked then, but of all times. The tendency of their conduct is to destroy the virtue, happiness, and peace of all with whom they come in contact.

Here again is shown that all mankind are under the guilt of sin, as a burden; and under the government and dominion of sin, as enslaved to it, to work wickedness. This is made plain by several passages of Scripture from the Old Testament, which describe the corrupt and depraved state of all men, till grace restrain or change them. Great as our advantages are, these texts describe multitudes who call themselves Christians. Their principles and conduct prove that there is no fear of God before their eyes. And where no fear of God is, no good is to be looked for.