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Isaiah 21:4

Albert Barnes
Notes on the Whole Bible

My heart panted - Margin, ‹My mind wandered.‘ The Hebrew word rendered ‹panted‘ (תעה tâ‛âh ) means to wander about; to stagger; to be giddy; and is applied often to one that staggers by being intoxicated. Applied to the heart, it means that it is disquieted or troubled. The Hebrew word “heart” here is to be taken in the sense of “mind.”

The night of my pleasure - There can be no doubt that the prophet here refers to the night of revelry and riot in which Babylon was taken. The prophet calls it the night of “his” pleasure, because he represents himself as being “in” Babylon when it should be taken, and, therefore, uses such language as an inhabitant of Babylon would use. “They” would call it the night of their pleasure, because it was set apart to feasting and revelry.

Hath he turned into fear - God has made it a night of consternation and alarm. The prophet here refers to the fact that Babylon would be taken by Cyrus during that night, and that consternation and alarm would suddenly pervade the affrighted and guilty city (see Daniel 5).

Matthew Henry
Concise Bible Commentary
Babylon was a flat country, abundantly watered. The destruction of Babylon, so often prophesied of by Isaiah, was typical of the destruction of the great foe of the New Testament church, foretold in the Revelation. To the poor oppressed captives it would be welcome news; to the proud oppressors it would be grievous. Let this check vain mirth and sensual pleasures, that we know not in what heaviness the mirth may end. Here is the alarm given to Babylon, when forced by Cyrus. An ass and a camel seem to be the symbols of the Medes and Persians. Babylon's idols shall be so far from protecting her, that they shall be broken down. True believers are the corn of God's floor; hypocrites are but as chaff and straw, with which the wheat is now mixed, but from which it shall be separated. The corn of God's floor must expect to be threshed by afflictions and persecutions. God's Israel of old was afflicted. Even then God owns it is his still. In all events concerning the church, past, present, and to come, we must look to God, who has power to do any thing for his church, and grace to do every thing that is for her good.
Ellen G. White
Prophets and Kings, 531

More than a century before, Inspiration had foretold that “the night of ... pleasure” during which king and counselors would vie with one another in blasphemy against God, would suddenly be changed into a season of fear and destruction. And now, in rapid succession, momentous events followed one another exactly as had been portrayed in the prophetic scriptures years before the principals in the drama had been born. PK 531.1

While still in the festal hall, surrounded by those whose doom has been sealed, the king is informed by a messenger that “his city is taken” by the enemy against whose devices he had felt so secure; “that the passages are stopped, ... and the men of war are affrighted.” Verses 31, 32. Even while he and his nobles were drinking from the sacred vessels of Jehovah, and praising their gods of silver and of gold, the Medes and the Persians, having turned the Euphrates out of its channel, were marching into the heart of the unguarded city. The army of Cyrus now stood under the walls of the palace; the city was filled with the soldiers of the enemy, “as with caterpillars” (verse 14); and their triumphant shouts could be heard above the despairing cries of the astonished revelers. PK 531.2

“In that night was Belshazzar the king of the Chaldeans slain,” and an alien monarch sat upon the throne. PK 531.3

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