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The wrath of God cometh - God is angry with such persons, and he inflicts on them the punishment which they deserve.

For which things‘ sake … - See the notes at Ephesians 5:6, where the same expression occurs.

God calls upon all who claim to be Christians to elevate the standard of righteousness, and to purify themselves even as He is pure. “Be ye holy in all manner of conversation.” “If ye then be risen with Christ, seek those things which are above.... Set your affection on things above, not on things on the earth. For ye are dead, and your life is hid with Christ in God. When Christ, who is our life, shall appear, then shall ye also appear with Him in glory. Mortify therefore your members which are upon the earth; fornication, uncleanness, inordinate affection, evil concupiscence, and covetousness, which is idolatry: for which things’ sake the wrath of God cometh on the children of disobedience.” “Wherefore gird up the loins of your mind, be sober, and hope to the end for the grace that is to be brought unto you at the revelation of Jesus Christ; as obedient children, not fashioning yourselves according to the former lusts in your ignorance;” for you are to walk in the light, while you have the light; “but as He which hath called you is holy, so be ye holy in all manner of conversation; because it is written, Be ye holy; for I am holy.”—Letter 6a, 1890. MM 147.1

The Christian physician is a minister of the highest order. He is a missionary. Those who through their skill and faithful, earnest effort, by wisdom from God, can relieve bodily pain, place themselves in such a relation to their patients that they can point them to the Soul Healer, who can say, “Thy sins be forgiven thee.” ... MM 147.2

“Mortify therefore your members which are upon the earth,” Paul wrote to the Colossians; “in the which ye also walked sometime, when ye lived in them. But now ye also put off all these: anger, wrath, malice, blasphemy, filthy communication out of your mouth.... Put on therefore, as the elect of God, holy and beloved, bowels of mercies, kindness, humbleness of mind, meekness, long-suffering; forbearing one another, and forgiving one another, if any man have a quarrel against any: even as Christ forgave you, so also do ye. And above all these things put on charity, which is the bond of perfectness. And let the peace of God rule in your hearts, to the which also ye are called in one body; and be ye thankful.” AA 477.1

The letter to the Colossians is filled with lessons of highest value to all who are engaged in the service of Christ, lessons that show the singleness of purpose and the loftiness of aim which will be seen in the life of him who rightly represents the Saviour. Renouncing all that would hinder him from making progress in the upward way or that would turn the feet of another from the narrow path, the believer will reveal in his daily life mercy, kindness, humility, meekness, forbearance, and the love of Christ. AA 477.2

The power of a higher, purer, nobler life is our great need. The world has too much of our thought, and the kingdom of heaven too little. AA 478.1

God will not accept a willful, imperfect obedience. Those who claim to be sanctified, and yet turn away their ears from hearing the law prove themselves to be the children of disobedience, whose carnal hearts are not subject to the law of God, and neither indeed can be.—Manuscript 40, 1894. 3SM 199.2