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See this passage illustrated in the notes at Mark 8:32

He spake that saying openly - With boldness or confidence, or without parables or figures, so that there could be no possibility of misunderstanding him.

Mark 8:38

Ashamed of me - Ashamed to own attachment to me on account of my lowly appearance and my poverty.

And of my words - My doctrines, my instructions.

This adulterous and sinful generation - This age given to wickedness, particularly to adultery.

In the glory of his Father - In the day of judgment. See the notes at Matthew 26:64. The meaning of this verse is, Whosoever shall refuse, through pride or wickedness, to acknowledge and serve Christ here, shall be excluded from his kingdom hereafter. He was lowly, meek, and despised; yet there was an inimitable beauty in his character even then. But he will come again in awful grandeur; not as the babe of Bethlehem, not as the man of Nazareth, but as the Son of God, in majesty and glory. They that would not acknowledge him here must be rejected by him there; they that would not serve him on earth will not enjoy his favor in heaven; they that would cast Him out and despise him must be cast out by him, and consigned to eternal, hopeless sorrow.

This chapter is based on Matthew 16:13-28; Mark 8:27-38; Luke 9:18-27.

The work of Christ on earth was hastening to a close. Before Him, in vivid outline, lay the scenes whither His feet were tending. Even before He took humanity upon Him, He saw the whole length of the path He must travel in order to save that which was lost. Every pang that rent His heart, every insult that was heaped upon His head, every privation that He was called to endure, was open to His view before He laid aside His crown and royal robe, and stepped down from the throne, to clothe His divinity with humanity. The path from the manger to Calvary was all before His eyes. He knew the anguish that would come upon Him. He knew it all, and yet He said, “Lo, I come: in the volume of the Book it is written of Me, I delight to do Thy will, O My God: yea, Thy law is within My heart.” Psalm 40:7, 8. DA 410.1

For whosoever will save his life shall lose it; but whosoever shall lose his life for my sake and the gospel's, the same shall save it. For what shall it profit a man, if he shall gain the whole world, and lose his own soul? Or what shall a man give in exchange for his soul? Mark 8:35-37. TMK 321.1

The Lord Jesus ... lifts up His voice to break the spell of infatuation upon human minds and asks the momentous question, “What shall it profit a man, if he shall gain the whole world, and lose his own soul?” ... TMK 321.2

Satan presented this inducement to Christ, knowing that if He accepted it, the world would never be ransomed. And under different guises he presents the same temptation to God's ministers today, knowing that those who are beguiled by it will be false to their trust. AA 366.1

It is not God's will that His ministers should seek to be rich. Regarding this, Paul wrote to Timothy: “The love of money is the root of all evil: which while some coveted after, they have erred from the faith, and pierced themselves through with many sorrows. But thou, O man of God, flee these things; and follow after righteousness, godliness, faith, love, patience, meekness.” By example as well as by precept, the ambassador for Christ is to “charge them that are rich in this world, that they be not high-minded, nor trust in uncertain riches, but in the living God, who giveth us richly all things to enjoy; that they do good, that they be rich in good works, ready to distribute, willing to communicate; laying up in store for themselves a good foundation against the time to come, that they may lay hold on eternal life.” 1 Timothy 6:10, 11, 17-19. AA 366.2

The experiences of the apostle Paul and his instruction regarding the sacredness of the minister's work are a source of help and inspiration to those engaged in the gospel ministry. Paul's heart burned with a love for sinners, and he put all his energies into the work of soul winning. There never lived a more self-denying, persevering worker. The blessings he received he prized as so many advantages to be used in blessing others. He lost no opportunity of speaking of the Saviour or of helping those in trouble. From place to place he went, preaching the gospel of Christ and establishing churches. Wherever he could find a hearing, he sought to counteract wrong, and to turn the feet of men and women into the path of righteousness. AA 367.1

Our Colleges Are Ordained of God—When I was shown by the angel of God that an institution should be established for the education of our youth, I saw that it would be one of the greatest means ordained of God for the salvation of souls.... If the influence in our college is what it should be, the youth who are educated there will be enabled to discern God and glorify Him in all His works; and while engaged in cultivating the faculties which God has given them, they will be preparing to render Him more efficient service.³ CG 329.1

The youth are to be encouraged to attend our schools, which should become more and more like the schools of the prophets. Our schools have been established by the Lord.⁴ CG 329.2

Advantages of Experience in School Home—To a great extent children who are to receive an education in our schools will make far more permanent advancement if separated from the family circle where they have received an erroneous education. It may be necessary for some families to locate where they can board their children and save expense, but in many cases it would prove a hindrance rather than a blessing to their children.⁵ CG 329.3

The rich man had all that money could procure, but he did not possess the riches that would have kept his account right with God. He had lived as if all that he possessed were his own. He had neglected the call of God and the claims of the suffering poor. But at length there comes a call which he cannot neglect. By a power which he cannot question or resist he is commanded to quit the premises of which he is no longer steward. The once-rich man is reduced to hopeless poverty. The robe of Christ's righteousness, woven in the loom of heaven, can never cover him. He who once wore the richest purple, the finest linen, is reduced to nakedness. His probation is ended. He brought nothing into the world, and he can take nothing out of it. COL 267.1

Christ lifted the curtain and presented this picture before priests and rulers, scribes and Pharisees. Look at it, you who are rich in this world's goods and are not rich toward God. Will you not contemplate this scene? That which is highly esteemed among men is abhorrent in the sight of God. Christ asks, “What shall it profit a man, if he shall gain the whole world, and lose his own soul? or what shall a man give in exchange for his soul?” Mark 8:36, 37. COL 267.2

Christ calls upon every one to consider. Make an honest reckoning. Put into one scale Jesus, which means eternal treasure, life, truth, heaven, and the joy of Christ in souls redeemed; put into the other every attraction the world can offer. Into one scale put the loss of your own soul, and the souls of those whom you might have been instrumental in saving; into the other, for yourself and for them, a life that measures with the life of God. Weigh for time and for eternity. While you are thus engaged, Christ speaks: “What shall it profit a man, if he shall gain the whole world, and lose his own soul?” Mark 8:36. COL 374.1

God desires us to choose the heavenly in place of the earthly. He opens before us the possibilities of a heavenly investment. He would give encouragement to our loftiest aims, security to our choicest treasure. He declares, “I will make a man more precious than fine gold; even a man than the golden wedge of Ophir.” Isaiah 13:12. When the riches that moth devours and rust corrupts shall be swept away, Christ's followers can rejoice in their heavenly treasure, the riches that are imperishable. COL 374.2

Better than all the friendship of the world is the friendship of Christ's redeemed. Better than a title to the noblest palace on earth is a title to the mansions our Lord has gone to prepare. And better than all the words of earthly praise will be the Saviour's words to His faithful servants, “Come, ye blessed of My Father, inherit the kingdom prepared for you from the foundation of the world.” Matthew 25:34. COL 374.3