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Having had perfect understanding - Παρηκολουθηκοτι ανωθεν, Having accurately traced up - entered into the very spirit of the work, and examined every thing to the bottom; in consequence of which investigation, I am completely convinced of the truth of the whole. Though God gives his Holy Spirit to all them who ask him, yet this gift was never designed to set aside the use of those faculties with which he has already endued the soul, and which are as truly his gifts as the Holy Spirit itself is. The nature of inspiration, in the case of St. Luke, we at once discover: he set himself, by impartial inquiry and diligent investigation, to find the whole truth, and to relate nothing but the truth; and the Spirit of God presided over and directed his inquiries, so that he discovered the whole truth, and was preserved from every particle of error.

From the very first - Ανωθεν, from their origin. Some think ανωθεν should, in this place, be translated from above; and that it refers to the inspiration by which St. Luke wrote. I prefer our translation, or, from the origin, which several good critics contend for, and which meaning it has in some of the best Greek writers. See Kypke.

Theophilus - As the literal import of this word is friend of God, Θεου φιλος, some have supposed that under this name Luke comprised all the followers of Christ, to whom, as friends of God, he dedicated this faithful history of the life, doctrine, death, and resurrection of our Lord. But this interpretation appears to have little solidity in it; for, if all the followers of Christ are addressed, why is the singular number used? and what good end could there be accomplished by using a feigned name? Besides, κρατιϚε, most excellent, could never be applied in this way, for it evidently designates a particular person, and one probably distinguished by his situation in life; though this does not necessarily follow from the title, which was often given in the way of friendship. Theophilus appears to have been some very reputable Greek or Roman, who was one of St. Luke's disciples. The first four verses seem a private epistle, sent by the evangelist with this history, which, having been carefully preserved by Theophilus, was afterwards found and published with this Gospel.

It seemed good - I thought it best; or, I have also determined. It seemed “to be called for” that there should be a full, authentic, and accurate account of these matters.

Having had perfect understanding … - The literal translation of the original here would be, “having exactly traced everything from the first;” or, “having, by diligent and careful investigation, “followed up” everything to the “source,” to obtain an accurate account of the matter.” This much better expresses the idea. Luke did not profess to have seen these things, and this expression is designed to show how he acquired his information. It was by “tracing up” every account until he became satisfied of its truth. Here observe,

1.That in religion God does not set aside our natural faculties. He calls us to look at evidence; to examine accounts; to make up our own minds. Nor will any man be convinced of the truth of religion who does “not” make investigation and set himself seriously to the task.

2.We see the nature of Luke‘s inspiration. It was consistent with his using his natural faculties or his own powers of mind in investigating the truth. God, by His Holy Spirit, presided over his faculties, directed them, and kept him from error.

In order - This word does not indicate that the exact order of time would be observed, for that is not the way in which he writes; but it means distinctly, particularly, in opposition to the confused and broken accounts to which he had referred before.

Most excellent Theophilus - The word Theophilus means “a friend of God,” or a pious man; and it has been supposed by some that Luke did not refer to any particular “individual,” but to any man that loved God; but there is no reason for this opinion. Significant names were very common, and there is no good reason to doubt that this was some individual known to Luke. The application of the title “most excellent “proves it further. It would not be given to an unknown man. The title “most excellent” has by some been supposed to be given to express his “character,” but it is rather to be considered as denoting rank or office. It occurs only in three other places in the New Testament, and is there given to men “in office” - to Felix and Festus, Acts 23:26; Acts 24:3; Acts 26:25. These titles express no quality of the “men,” but belong to the “office;” and we may hence learn that it is not improper for Christians, in giving honor to whom honor is due, to address men in office by their customary titles, even if their moral character be altogether unworthy of it. Who “Theophilus” was is unknown. It is probable that he was some distinguished Roman or Greek who had been converted, who was a friend of Luke, and who had requested an account of these things. It is possible that this preface might have been sent to him as a private letter with the gospel, and Theophilus chose to have them published together.

Luke, the writer of the Gospel that bears his name, was a medical missionary. In the Scriptures he is called “the beloved physician.” Colossians 4:14. The apostle Paul heard of his skill as a physician, and sought him out as one to whom the Lord had entrusted a special work. He secured his co-operation, and for some time Luke accompanied him in his travels from place to place. After a time, Paul left Luke at Philippi, in Macedonia. Here he continued to labor for several years, both as a physician and as a teacher of the gospel. In his work as a physician he ministered to the sick, and then prayed for the healing power of God to rest upon the afflicted ones. Thus the way was opened for the gospel message. Luke's success as a physician gained for him many opportunities for preaching Christ among the heathen. It is the divine plan that we shall work as the disciples worked. Physical healing is bound up with the gospel commission. In the work of the gospel, teaching and healing are never to be separated. MH 140.1

The work of the disciples was to spread a knowledge of the gospel. To them was committed the work of proclaiming to all the world the good news that Christ brought to men. That work they accomplished for the people of their time. To every nation under heaven the gospel was carried in a single generation. MH 141.1

Book of Acts, Instruction for Today—The whole of the book of Acts should receive careful study. It is full of precious instruction; it records experiences in evangelistic work, the teachings of which we need in our work today. This is wonderful history; it deals with the highest education, which the students in our schools are to receive (Letter 100, 1909). 6BC 1051.1

On the sickbed Christ is often accepted and confessed; and this will be done oftener in the future than it has been in the past, for a quick work will the Lord do in our world. Words of wisdom are to be on the lips of the physician, and Christ will water the seed sown, causing it to bring forth fruit unto eternal life. 6T 233.1

We lose the most precious opportunities by neglecting to speak a word in season. Too often a precious talent that ought to produce a thousandfold is left unused. If the golden privilege is not watched for, it will pass. Something was allowed to prevent the physician from doing his appointed work as a minister of righteousness. 6T 233.2

There are none too many godly physicians to minister in their profession. There is much work to be done, and ministers and doctors are to work in perfect union. Luke, the writer of the Gospel that bears his name, is called “the beloved physician,” and those who do a work similar to that which he did are living out the gospel. 6T 233.3