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There shall be a great cry - Of the dying and for the dead. See more on this subject, Exodus 12:30; (note).

When the demand for Israel's release had been first presented to the king of Egypt, the warning of the most terrible of the plagues had been given. Moses was directed to say to Pharaoh, “Thus saith the Lord, Israel is My son, even My first-born: and I say unto thee, Let My son go, that he may serve Me: and if thou refuse to let him go, behold, I will slay thy son, even thy first-born.” Exodus 4:22, 23. Though despised by the Egyptians, the Israelites had been honored by God, in that they were singled out to be the depositaries of His law. In the special blessings and privileges accorded them, they had pre-eminence among the nations, as the first-born son had among brothers. PP 273.1

The judgment of which Egypt had first been warned, was to be the last visited. God is long-suffering and plenteous in mercy. He has a tender care for the beings formed in His image. If the loss of their harvests and their flocks and herds had brought Egypt to repentance, the children would not have been smitten; but the nation had stubbornly resisted the divine command, and now the final blow was about to fall. PP 273.2

Moses had been forbidden, on pain of death, to appear again in Pharaoh's presence; but a last message from God was to be delivered to the rebellious monarch, and again Moses came before him, with the terrible announcement: “Thus saith the Lord, About midnight will I go out into the midst of Egypt: and all the first-born in the land of Egypt shall die, from the first-born of Pharaoh that sitteth upon his throne, even unto the first-born of the maidservant that is behind the mill; and all the first-born of beasts. And there shall be a great cry throughout all the land of Egypt, such as there was none like it, nor shall be like it any more. But against any of the children of Israel shall not a dog move his tongue, against man or beast: that ye may know how that the Lord doth put a difference between the Egyptians and Israel. And all these thy servants shall come down unto me, and bow down themselves unto me, saying, Get thee out, and all the people that follow thee: and after that I will go out.” PP 273.3

The history of the wilderness life of Israel was chronicled for the benefit of the Israel of God to the close of time. The record of God's dealings with the wanderers of the desert in all their marchings to and fro, in their exposure to hunger, thirst, and weariness, and in the striking manifestations of His power for their relief, is fraught with warning and instruction for His people in all ages. The varied experience of the Hebrews was a school of preparation for their promised home in Canaan. God would have His people in these days review with a humble heart and teachable spirit the trials through which ancient Israel passed, that they may be instructed in their preparation for the heavenly Canaan. PP 293.1

Many look back to the Israelites, and marvel at their unbelief and murmuring, feeling that they themselves would not have been so ungrateful; but when their faith is tested, even by little trials, they manifest no more faith or patience than did ancient Israel. When brought into strait places, they murmur at the process by which God has chosen to purify them. Though their present needs are supplied, many are unwilling to trust God for the future, and they are in constant anxiety lest poverty shall come upon them, and their children shall be left to suffer. Some are always anticipating evil or magnifying the difficulties that really exist, so that their eyes are blinded to the many blessings which demand their gratitude. The obstacles they encounter, instead of leading them to seek help from God, the only Source of strength, separate them from Him, because they awaken unrest and repining. PP 293.2

It was very hard for the Egyptian king and a proud and idolatrous people to yield to the requirements of the God of heaven. Very slow was the king of Egypt to yield. While under most grievous affliction he would yield a little; but when the affliction was removed, he would take back all he had granted. Thus, plague after plague was brought upon Egypt, and he yielded no more than he was compelled to by the dreadful visitations of God's wrath. The king even persisted in his rebellion after Egypt had been ruined. SR 118.1

Moses and Aaron related to Pharaoh the nature and effect of each plague which should follow his refusal to let Israel go. Every time he saw these plagues come exactly as he was told they would come; yet he would not yield. First, he would only grant them permission to sacrifice to God in the land of Egypt; then, after Egypt had suffered by God's wrath, he granted that the men alone should go. After Egypt had been nearly destroyed by the plague of the locusts, then he granted that their children and their wives might go also, but would not let their cattle go. Moses then told the king that the angel of God would slay their first-born. SR 118.2

Every plague had come a little closer and more severe, and this was to be more dreadful than any before it. But the proud king was exceedingly angry, and humbled not himself. And when the Egyptians saw the great preparations being made among the Israelites for that dreadful night, they ridiculed the token of blood upon their doorposts. SR 118.3