A wise man's heart is at his right hand - As the right hand is ordinarily the best exercised, strongest, and most ready, and the left the contrary, they show,
2. The want of prudence and management in the fool, who has no restraint on his passions, and no rule or guard upon his tongue. The right hand and the left are used in Scripture to express good and evil. The wise man is always employed in doing good; the fool, in nonsense or evil.
The metaphor perhaps means “A wise man‘s sense is in its place, ready to help and protect him; but a fool‘s sense is missing when it is wanted, and so is useless.”