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The mouth of the wicked and - the deceitful are opened against me - Many persons are continually uttering calumnies against me. Thou knowest my heart and its innocence; vindicate my uprightness against these calumniators.

For the mouth of the wicked and the mouth of the deceitful - literally, “The mouth of wickedness, and the mouth of deceit.” This acquaints us with the nature of the wrong which had been done him. It was slander; undeserved reproach.

Are opened against me - Margin, “have opened;” that is, have opened themselves.

They have spoken against me with a lying tongue - They have accused me of things which are not true; they have made false charges against me. David, as has not been uncommon with good people, was called repeatedly to this trial.

It is the unspeakable comfort of all believers, that whoever is against them, God is for them; and to him they may apply as to one pleased to concern himself for them. David's enemies laughed at him for his devotion, but they could not laugh him out of it.