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Thou shalt go forth from him, and thine hands upon thine head - Thou shalt find all thy confidence in vain, - thy hope disappointed; - and thy state reduced to desperation. The hand being placed on the head was the evidence of deep sorrow, occasioned by utter desolation. See the case of Tamar, when ruined and abandoned by her brother Amnon, 2 Samuel 13:19.

Thou shalt not prosper in them - They shall all turn to thy disadvantage; and this as we shall see in the history of this people, was literally fulfilled. O what a grievous and bitter thing it is to sin against the Lord, and have him for an enemy!

From him - From it, from this Egypt, which though fem. as a land, yet as a people may be used as a masc. (compare Jeremiah 46:8). Now that Nineveh is trembling before the armies of Cyaxares and Nabopalassar, thou hastenest to Egypt, hoping to rest upon her strength: but thou shalt retrace thy steps, with thy hands clasped upon thy head, disgraced and discarded.

Confidences - Those in whom thou confidest.

In them - literally, “with respect to them.”

The nation had not been wrought upon by the judgements of God, but sought to justify themselves. The world is, to those who make it their home and their portion, a wilderness and a land of darkness; but those who dwell in God, have the lines fallen to them in pleasant places. Here is the language of presumptuous sinners. The Jews had long thrown off serious thoughts of God. How many days of our lives pass without suitable remembrance of him! The Lord was displeased with their confidences, and would not prosper them therein. Men employ all their ingenuity, but cannot find happiness in the way of sin, or excuse for it. They may shift from one sin to another, but none ever hardened himself against God, or turned from him, and prospered.