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Isaiah 6:11

Adam Clarke
Bible Commentary

Be utterly desolate "Be left" - For תשאה tishaeh, the Septuagint and Vulgate read תשאר tishshaer .

Albert Barnes
Notes on the Whole Bible

How long - The prophet did not dare to pray that this effect should not follow. He asked merely therefore “how long” this state of things must continue; how long this message was to be delivered, and how long it should be attended with these painful effects.

Until the cities … - They will remain perverse and obstinate until the land is completely destroyed by divine judgments. Still the truth is to be proclaimed, though it is known it will have no effect in reforming the nation. This refers, doubtless, to the destruction that was accomplished by the Babylonians.

The houses without man - This is strong language, denoting the certain and widespread desolation that should come upon the nation.

Matthew Henry
Concise Bible Commentary
God sends Isaiah to foretell the ruin of his people. Many hear the sound of God's word, but do not feel the power of it. God sometimes, in righteous judgment, gives men up to blindness of mind, because they will not receive the truth in the love of it. But no humble inquirer after Christ, need to fear this awful doom, which is a spiritual judgment on those who will still hold fast their sins. Let every one pray for the enlightening of the Holy Spirit, that he may perceive how precious are the Divine mercies, by which alone we are secured against this dreadful danger. Yet the Lord would preserve a remnant, like the tenth, holy to him. And blessed be God, he still preserves his church; however professors or visible churches may be lopped off as unfruitful, the holy seed will shoot forth, from whom all the numerous branches of righteousness shall arise.