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Psalms 22:10

King James Version (KJV)
Albert Barnes
Notes on the Whole Bible

I was cast upon thee from the womb - Upon thy protection and care. This, too, is an argument for the divine interposition. He had been, as it were, thrown early in life upon the protecting care of God. In some special sense he had been more unprotected and defenseless than is common at that period of life, and he owed his preservation then entirely to God. This, too, may have passed through the mind of the Redeemer on the cross. In those sad and desolate moments he may have recalled the scenes of his early life - the events which had occurred in regard to him in his early years; the poverty of his mother, the manger, the persecution by Herod, the flight into Egypt, the return, the safety which he then enjoyed from persecution in a distant part of the land of Palestine, in the obscure and unknown village of Nazareth. This too may have occurred to his mind as a reason why God should interpose and deliver him from the dreadful darkness which had come over him now.

Thou art my God from my mother‘s belly - Thou hast been my God from my very childhood. He had loved God as such; be had obeyed him as such; he had trusted him as such; and he now pleads this as a reason why God should interpose for him.

Matthew Henry
Concise Bible Commentary
The Spirit of Christ, which was in the prophets, testifies in this psalm, clearly and fully, the sufferings of Christ, and the glory that should follow. We have a sorrowful complaint of God's withdrawings. This may be applied to any child of God, pressed down, overwhelmed with grief and terror. Spiritual desertions are the saints' sorest afflictions; but even their complaint of these burdens is a sign of spiritual life, and spiritual senses exercised. To cry our, My God, why am I sick? why am I poor? savours of discontent and worldliness. But, "Why hast thou forsaken me?" is the language of a heart binding up its happiness in God's favour. This must be applied to Christ. In the first words of this complaint, he poured out his soul before God when he was upon the cross, Mt 27:46. Being truly man, Christ felt a natural unwillingness to pass through such great sorrows, yet his zeal and love prevailed. Christ declared the holiness of God, his heavenly Father, in his sharpest sufferings; nay, declared them to be a proof of it, for which he would be continually praised by his Israel, more than for all other deliverances they received. Never any that hoped in thee, were made ashamed of their hope; never any that sought thee, sought thee in vain. Here is a complaint of the contempt and reproach of men. The Saviour here spoke of the abject state to which he was reduced. The history of Christ's sufferings, and of his birth, explains this prophecy.