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Jeremiah 45:3

Adam Clarke
Bible Commentary

Thou didst say, Wo is me now! - All that were the enemies of Jeremiah became his enemies too; and he needed these promises of support.

The Lord hath added grief to my sorrow - He had mourned for the desolations that were coming on his country, and now he mourns for the dangers to which he feels his own life exposed; for we find, from Jeremiah 36:26, that the king had given commandment to take both Baruch and Jeremiah, in order that they might be put to death at the instance of his nobles.

Albert Barnes
Notes on the Whole Bible

Grief to my sorrow - Baruch‘s sorrow is caused by the sinfulness of the Jewish nation, to which God adds grief by showing how severely it will be punished.

I fainted in - Or, “am weary with” Psalm 6:6.